Investigating Mitochondria Transfer in Glioblastoma (Podcast)
Glioblastoma, the most common primary malignant brain tumor, typically presents late, is difficult to treat and has a poor prognosis. “You can count on one hand the number of FDA-approved drugs for...
View ArticleDiscovering the Clever Way that Flaviviruses Boost Their Own Replication
A Cleveland Clinic-led research team has identified a key protein-modifying mechanism that the Zika virus (ZIKV) and other mosquito-transmitted flaviviruses use to hijack infected host cells and...
View ArticleClik here to view.
Researchers Identify Promising Compound for IBD Treatment
A team of researchers from Cleveland Clinic’s Lerner Research Institute, Johns Hopkins University School of Medicine and Johns Hopkins Drug Discovery has synthesized and tested a new class of...
View ArticleAdvanced Computational and Imaging Tools Yield Insights Into Learning and...
Cutting-edge optical imaging techniques, advanced computational methods and complex analysis of animal behavior are being employed to better understand — and even manipulate — neurological mechanisms...
View ArticleClik here to view.
An All-Fronts Approach to Understanding and Overcoming Alzheimer’s Disease
Although more than a century has passed since Alzheimer’s disease (AD) was first characterized, prevention and effective treatments have remained elusive. In an effort to spur progress against this...
View ArticleBlood-Based Biomarkers for Alzheimer’s Disease in Women (Podcast)
Nearly two-thirds of people living with Alzheimer’s disease are women — a disproportionate share that suggests a need to identify sex-specific biomarkers to aid in early detection and diagnosis. With...
View ArticleA Unique Opportunity to Explore Quantum Computing’s Potential
Quantum computing’s powerful data analysis capabilities are poised to transform healthcare by greatly accelerating the pace of biomedical discoveries. Yet companies hoping to leverage this unique...
View ArticleMicroglial Immunometabolism Endophenotypes Implicated in Sex Differences in...
Sex-related differences in Alzheimer’s disease (AD) pathogenesis and disease progression may be due in part to sex-specific differences in immune responses, cellular metabolism and microglial...
View ArticleCan Boosting Hydrogen Sulfide Bolster Standard-of-Care Glioblastoma Therapy...
New Cleveland Clinic research efforts are exploring the cancer-suppressing effects of endogenous hydrogen sulfide (H2S) in glioblastoma and whether aging-induced decreases in H2S can be effectively...
View ArticleNoninvasive Technology Enhances Ability to Map Brain Activity to Track...
A research team led by Cleveland Clinic and Oregon Health and Science University (OHSU) investigators has developed a new method for mapping the electrical paths that connect and coordinate various...
View Article
